CTCAE Grade 2 Oral Cavity GI Fistula

Symptomatic; altered GI function (e.g., altered dietary habits, diarrhea, or GI fluid loss); IV fluids indicated <24 hrs (NCI Thesaurus/CTCAE)

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CTCAE Grade 2 Optic Disc Edema

Decreased visual acuity (20/40 or better); visual field defect present

CTCAE Grade 2 Opportunistic Infection

Localized, local intervention indicated

CTCAE Grade 2 Ophthalmoplegia and Diplopia

Symptomatic and interfering with function but not interfering with ADL

CTCAE Grade 2 Ocular Surface Disease

Symptomatic, interfering with function but not interfering with ADL; topical antibiotics or other topical intervention indicated

CTCAE Grade 2 Ocular Muscle Weakness Not Due to Neuropathy

Symptomatic and interfering with function, but not interfering with ADL

CTCAE Grade 2 Obesity

BMI 25 - 29.9 kg/m(2)