CTCAE Grade 2 Other Auditory and Ear

BMD t-score < -2.5; loss of height <2 cm; anti-osteoporotic therapy indicated

Decrease in orgasmic response requiring intervention

Moderate pain; pain or analgesics interfering with function, but not interfering with ADL

Partial resection of injured organ/structure indicated

Symptomatic, tube thoracostomy or medical management indicated; associated with altered respiratory function but not interfering with ADL