CTCAE Grade 2 Proptosis and Enophthalmos

Symptomatic and interfering with function, but not interfering with ADL (NCI Thesaurus/CTCAE)

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CTCAE Grade 2 Prolonged QTc Interval

QTc >0.47 - 0.50 second; >=0.06 second above baseline

CTCAE Grade 2 Prolonged Intubation After Pulmonary Resection

Extubated within 24 - 72 hrs postoperatively

CTCAE Grade 2 Prolonged Chest Tube Drainage or Air Leak After Pulmonary Resection

Sclerosis or additional tube thoracostomy indicated

CTCAE Grade 2 Prolapse of Gastrointestinal Stoma

Extraordinary local care or maintenance; minor revision indicated

CTCAE Grade 2 Proctitis

Symptoms not interfering with ADL; medical intervention indicated

CTCAE Grade 2 Precocious Puberty

Physical signs of puberty <7 years for females, <9 years for males