CTCAE Grade 2 Rectum Infection with Unknown Absolute Neutrophil Count

Localized, local intervention indicated (NCI Thesaurus/CTCAE)

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CTCAE Grade 2 Rectum Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils

Localized, local intervention indicated

CTCAE Grade 2 Rectum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils

Localized, local intervention indicated

CTCAE Grade 2 Rectum Hemorrhage

Symptomatic and medical intervention or minor cauterization indicated

CTCAE Grade 2 Rectum Fistula

Symptomatic; altered GI function (e.g., altered dietary habits, diarrhea, or GI fluid loss); IV fluids indicated <24 hrs

CTCAE Grade 2 Rectal Varices Hemorrhage

Symptomatic and medical intervention or minor cauterization indicated

CTCAE Grade 2 Rash Hand or Foot Skin Reaction

Skin changes (e.g., peeling, blisters, bleeding, edema) or pain, not interfering with function