CTCAE Grade 3 Anal or Perianal Infection with Unknown Absolute Neutrophil Count

IV antibiotic, antifungal, or antiviral intervention indicated; interventional radiology or operative intervention indicated (NCI Thesaurus/CTCAE)

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CTCAE Grade 3 Anal or Perianal Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils

IV antibiotic, antifungal, or antiviral intervention indicated; interventional radiology or operative intervention indicated

CTCAE Grade 3 Anal or Perianal Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils

IV antibiotic, antifungal, or antiviral intervention indicated; interventional radiology or operative intervention indicated

CTCAE Grade 3 Anal Incontinence

Interfering with ADL; operative intervention indicated

CTCAE Grade 3 Amylase

2.0 - 5.0 x ULN

CTCAE Grade 3 Allergic Reaction and Hypersensitivity Including Drug Fever

Symptomatic bronchospasm, with or without urticaria; parenteral medication(s) indicated; allergy-related edema/angioedema; hypotension

CTCAE Grade 3 Alkaline phosphatase

5.0 - 20.0 x ULN