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CTCAE Grade 3 Carbon Monoxide Diffusion Capacity
<50 - 25% of predicted value (NCI Thesaurus/CTCAE)
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Severe pain; pain or analgesics severely interfering with ADL
Moderate to major debridement or reconstruction indicated
Interfering with ADL; stridor or endoscopic intervention indicated (e.g., stent, laser)
Complete resection or reconstruction of injured organ/structure indicated
IV antibiotic, antifungal, or antiviral intervention indicated; interventional radiology or operative intervention indicated
IV antibiotic, antifungal, or antiviral intervention indicated; interventional radiology or operative intervention indicated
