CTCAE Grade 3 Cardiac Ischemia or Infarction

Symptomatic and testing consistent with ischemia; unstable angina; intervention indicated (NCI Thesaurus/CTCAE)

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CTCAE Grade 3 Cardiac and Heart Pain

Severe pain; pain or analgesics severely interfering with ADL

CTCAE Grade 3 Carbon Monoxide Diffusion Capacity

<50 - 25% of predicted value

CTCAE Grade 3 Buttock Pain

Severe pain; pain or analgesics severely interfering with ADL

CTCAE Grade 3 Burn

Moderate to major debridement or reconstruction indicated

CTCAE Grade 3 Bronchus Obstruction and Stenosis

Interfering with ADL; stridor or endoscopic intervention indicated (e.g., stent, laser)

CTCAE Grade 3 Bronchus Intra-Operative Injury

Complete resection or reconstruction of injured organ/structure indicated