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CTCAE Grade 3 Cardiac Troponin I
Levels consistent with unstable angina as defined by the manufacturer (NCI Thesaurus/CTCAE)
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Symptomatic and testing consistent with ischemia; unstable angina; intervention indicated
Severe pain; pain or analgesics severely interfering with ADL
<50 - 25% of predicted value
Severe pain; pain or analgesics severely interfering with ADL
Moderate to major debridement or reconstruction indicated
Interfering with ADL; stridor or endoscopic intervention indicated (e.g., stent, laser)