CTCAE Grade 3 Cardiac Troponin T

Levels consistent with unstable angina as defined by the manufacturer

Symptomatic and testing consistent with ischemia; unstable angina; intervention indicated

Severe pain; pain or analgesics severely interfering with ADL

<50 - 25% of predicted value

Severe pain; pain or analgesics severely interfering with ADL

Moderate to major debridement or reconstruction indicated