CTCAE Grade 3 Esophagus Necrosis

Inability to aliment adequately by GI tract (e.g., requiring enteral or parenteral nutrition); interventional radiology, endoscopic, or operative intervention indicated (NCI Thesaurus/CTCAE)

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CTCAE Grade 3 Esophagus Mucositis or Stomatitis by Functional or Symptomatic Classification

Upper aerodigestive tract sites: Symptomatic and unable to adequately aliment or hydrate orally; respiratory symptoms interfering with ADL Lower GI sites: Stool…

CTCAE Grade 3 Esophagus Mucositis or Stomatitis by Clinical Examination Classification

Erythema of the mucosa

CTCAE Grade 3 Esophagus Leak

Symptomatic and interfering with GI function; invasive or endoscopic intervention indicated

CTCAE Grade 3 Esophagus Intra-Operative Injury

Complete resection or reconstruction of injured organ/structure indicated

CTCAE Grade 3 Esophagus Infection with Unknown Absolute Neutrophil Count

IV antibiotic, antifungal, or antiviral intervention indicated; interventional radiology or operative intervention indicated

CTCAE Grade 3 Esophagus Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils

IV antibiotic, antifungal, or antiviral intervention indicated; interventional radiology or operative intervention indicated