CTCAE Grade 3 Female Genital Tract Fistula

Severe fatigue interfering with ADL

Symptomatic and altered organ function (e.g., sepsis or hydronephrosis, or renal dysfunction); operative intervention indicated

Symptomatic, operative intervention indicated

Symptomatic and altered organ function (e.g., sepsis or hydronephrosis, or renal dysfunction); operative intervention indicated

Symptomatic, interfering with GU function; invasive or endoscopic intervention indicated