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CTCAE Grade 3 Flu-Like Syndrome
Severe symptoms interfering with ADL (NCI Thesaurus/CTCAE)
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<0.5 - 0.25 x LLN or 50 - <75% decrease from baseline
40.0 degrees C (>104.0 degrees F) for <=24 hrs
<50 - 25% of predicted value
