CTCAE Grade 3 Gallbladder Fistula

Symptomatic and severely altered GI function (e.g., altered dietary habits, diarrhea, or GI fluid loss); IV fluids, tube feedings, or TPN indicated >=24 hrs (NCI Thesaurus/CTCAE)

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CTCAE Grade 3 Fracture

Symptomatic and displaced or open wound with bone exposure; operative intervention indicated

CTCAE Grade 3 Foreign Body Infection with Unknown Absolute Neutrophil Count

IV antibiotic, antifungal, or antiviral intervention indicated; interventional radiology or operative intervention indicated

CTCAE Grade 3 Foreign Body Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils

IV antibiotic, antifungal, or antiviral intervention indicated; interventional radiology or operative intervention indicated

CTCAE Grade 3 Foreign Body Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils

IV antibiotic, antifungal, or antiviral intervention indicated; interventional radiology or operative intervention indicated

CTCAE Grade 3 Flu-Like Syndrome

Severe symptoms interfering with ADL

CTCAE Grade 3 Flashing Lights and Floaters in Vision

Symptomatic and interfering with ADL