CTCAE Grade 3 Gastrointestinal Leak NOS

Symptomatic and severely altered gastric function (e.g., inadequate oral caloric or fluid intake); IV fluids, tube feedings, or TPN indicated >24 hrs…

5.0 - 20.0 x ULN

IV fluids, tube feedings, or TPN indicated >=24 hrs; operative intervention indicated

Severe pain; pain or analgesics severely interfering with ADL

Symptomatic and severely altered GI function (e.g., altered dietary habits, vomiting, diarrhea, or GI fluid loss); IV fluids, tube feedings, or TPN…

Inability to aliment adequately by GI tract (e.g., requiring enteral or parenteral nutrition); interventional radiology, endoscopic, or operative intervention indicated