CTCAE Grade 3 Lower Extremity Artery Intra-Operative Injury

Complete resection or reconstruction of injured organ/structure indicated (NCI Thesaurus/CTCAE)

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CTCAE Grade 3 Lower Extremity Artery Injury

Symptomatic interfering with ADL; repair or revision indicated

CTCAE Grade 3 Low Serum Bicarbonate

<11 - 8 mmol/L

CTCAE Grade 3 Local Complication of Device and Prosthesis

Symptomatic, interfering with ADL; operative intervention indicated (e.g., hardware/device replacement or removal, reconstruction)

CTCAE Grade 3 Liver Pain

Severe pain; pain or analgesics severely interfering with ADL

CTCAE Grade 3 Liver Intra-Operative Injury

Complete resection or reconstruction of injured organ/structure indicated

CTCAE Grade 3 Liver Infection with Unknown Absolute Neutrophil Count

IV antibiotic, antifungal, or antiviral intervention indicated; interventional radiology or operative intervention indicated