CTCAE Grade 3 Mediastinum Hemorrhage

Transfusion, interventional radiology, endoscopic, or operative intervention indicated; radiation therapy (i.e., hemostasis of bleeding site) (NCI Thesaurus/CTCAE)

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CTCAE Grade 3 Masculinization of Female

CTCAE Grade 3 Malabsorption

Inability to aliment adequately via GI tract (i.e., TPN indicated)

CTCAE Grade 3 Major Visceral Vein Intra-Operative Injury

Complete resection or reconstruction of injured organ/structure indicated

CTCAE Grade 3 Major Visceral Artery Intra-Operative Injury

Complete resection or reconstruction of injured organ/structure indicated

CTCAE Grade 3 Lymphopenia

<500 - 200 mm(3) <0.5 - 0.2 x 10e9 /L

CTCAE Grade 3 Lymphocele

Symptomatic and interventional radiology or operative intervention indicated