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CTCAE Grade 3 Neuroendocrine ACTH Deficiency
Symptoms interfering with ADL; hospitalization indicated (NCI Thesaurus/CTCAE)
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Severe pain; pain or analgesics severely interfering with ADL
Operative debridement or other invasive intervention indicated (e.g., hyperbaric oxygen)
Severe pain; pain or analgesics severely interfering with ADL
Complete resection or reconstruction of injured organ/structure indicated
IV antibiotic, antifungal, or antiviral intervention indicated; interventional radiology or operative intervention indicated
IV antibiotic, antifungal, or antiviral intervention indicated; interventional radiology or operative intervention indicated
