CTCAE Grade 4 Middle Ear Intra-Operative Injury

Life threatening consequences; disabling (NCI Thesaurus/CTCAE)

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Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)

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Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)

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Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)

CTCAE Grade 4 Metabolic or Respiratory Alkalosis

pH >7.5 with life-threatening consequences

CTCAE Grade 4 Metabolic or Respiratory Acidosis

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CTCAE Grade 4 Meninges Intra-Operative Injury

Life threatening consequences; disabling