CTCAE Grade 4 Pancreatic Endocrine Glucose Intolerance

Life-threatening consequences (e.g., ketoacidosis, hyperosmolar non-ketotic coma) (NCI Thesaurus/CTCAE)

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CTCAE Grade 4 Pancreatic Duct Intra-Operative Injury

Life threatening consequences; disabling

CTCAE Grade 4 Pancreas or Pancreatic Duct Stricture or Stenosis

Life-threatening consequences; operative intervention requiring complete organ resection (e.g., total colectomy)

CTCAE Grade 4 Pancreas Necrosis

Life-threatening consequences; operative intervention requiring complete organ resection (e.g., total colectomy)

CTCAE Grade 4 Pancreas Leak

CTCAE Grade 4 Pancreas Intra-Operative Injury

Life threatening consequences; disabling

CTCAE Grade 4 Pancreas Infection with Unknown Absolute Neutrophil Count

Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)