CTCAE Grade 4 Peripheral Arterial Ischemia

Life-threatening, disabling and/or associated with end organ damage (e.g., limb loss) (NCI Thesaurus/CTCAE)

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CTCAE Grade 4 Pericarditis

Life-threatening consequences; emergency intervention indicated

CTCAE Grade 4 Penis Pain

CTCAE Grade 4 Penis Intra-Operative Injury

Life threatening consequences; disabling

CTCAE Grade 4 Penis Infection with Unknown Absolute Neutrophil Count

Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)