CTCAE Grade 4 Pleura Infection with Unknown Absolute Neutrophil Count

Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis) (NCI Thesaurus/CTCAE)

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CTCAE Grade 4 Pleura Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils

Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)

CTCAE Grade 4 Pleura Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils

Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)

CTCAE Grade 4 Pleura Hemorrhage

Life-threatening consequences; major urgent intervention indicated

CTCAE Grade 4 Pleura Fistula

Life-threatening consequences; operative intervention with thoracoplasty, chronic open drainage or multiple thoracotomies indicated

CTCAE Grade 4 Platelets

<25,000/mm(3) <25.0 x 10e9 /L

CTCAE Grade 4 Pituitary Intra-Operative Injury

Life threatening consequences; disabling