CTCAE Grade 4 Testes Perforation

Life-threatening consequences or organ failure; operative intervention requiring organ resection indicated (NCI Thesaurus/CTCAE)

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CTCAE Grade 4 Testes Obstruction

Life-threatening consequences; organ failure or operative intervention requiring complete organ resection indicated

CTCAE Grade 4 Testes Hemorrhage

Life-threatening consequences; major urgent intervention indicated

CTCAE Grade 4 Tendon Intra-Operative Injury

Life threatening consequences; disabling

CTCAE Grade 4 Teeth Intra-Operative Injury

Life threatening consequences; disabling

CTCAE Grade 4 Syncope

CTCAE Grade 4 Supraventricular Tachycardia

Life-threatening (e.g., arrhythmia associated with CHF, hypotension, syncope, shock)