CTCAE Grade 4 Urethra Stricture or Stenosis

Life-threatening consequences; organ failure or operative intervention requiring organ resection indicated (NCI Thesaurus/CTCAE)

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CTCAE Grade 4 Urethra Perforation

Life-threatening consequences or organ failure; operative intervention requiring organ resection indicated

CTCAE Grade 4 Urethra Pain

CTCAE Grade 4 Urethra Obstruction

Life-threatening consequences; organ failure or operative intervention requiring complete organ resection indicated

CTCAE Grade 4 Urethra Leak

CTCAE Grade 4 Urethra Intra-Operative Injury

Life threatening consequences; disabling

CTCAE Grade 4 Urethra Infection with Unknown Absolute Neutrophil Count

Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)