CTCF wt Allele

Human CTCF is located within 16q21-22.3 and is approximately 77 kb in length. This allele, which encodes transcriptional repressor CTCF protein, may play a role in transcriptional repression and establishment of heterochromatin boundaries. (NCI Thesaurus)

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CTCF is central to signaling pathways in immature B cells elicited by cross-linking the Ig BCR and stimulation with TGF. Both stimuli…

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This gene is involved in epigenetic control of gene expression.

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