CTTN wt Allele

Human CTTN wild-type allele is located within 11q13 and is approximately 38 kb in length. This allele, which encodes Src substrate cortactin protein, plays a role in regulating the interactions between components of adherens-type junctions and in organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. Aberrant regulation of this gene contributes to tumor cell invasion and metastasis, and it is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. (NCI Thesaurus)

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CTTN Gene

This gene plays a role in epithelial cytoskeletal organization and in cellular adhesion.

CTSZ wt Allele

Human CTSZ wild-type allele is located within 20q13 and is approximately 12 kb in length. This allele, which encodes cathepsin Z protein,…

CTSZ Gene

This gene plays a role in intracellular protein catabolism.

CTSS wt Allele

Human CTSS wild-type allele is located in the vicinity of 1q21 and is approximately 36 kb in length. This allele, which encodes…

CTSS Gene

This gene is involved in the proteolysis of antigenic proteins.

CTSL1 wt Allele

Human CTSL wild-type allele is located within 9q21-q22 and is approximately 5 kb in length. This allele, which encodes cathepsin L protein,…