Health / Medical Topics |
Cullin Family Gene
Cullin Family Genes encode Cullin Family Proteins, which are components of SCF ubiquitin ligase complexes or E3 ubiquitin ligase complexes with elongin BC complexes and other factors, involved in ubiquitination and proteasomal degradation of target cell cycle, signal transduction, and transcription proteins. Cullins may act in these multisubunit complexes as a scaffold for substrates and ubiquitin-conjugating enzymes and interact with RBX1, RNF7, CYCE, and/or TIP120A/CAND1. (NCI Thesaurus)
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Endoscopic examination of a woman's pelvic organs using a culdoscope inserted through the vagina.
An endoscope for examination of a woman's pelvic organs through the vagina.
Human CUL5 wild-type allele is located within 11q22-q23 and is approximately 98 kb in length. This allele, which encodes cullin-5 protein, plays…
This gene plays a role in cell cycle arrest, DNA repair and protein degradation.
Human CUL4B wild-type allele is located in the vicinity of Xq23 and is approximately 51 kb in length. This allele, which encodes…
This gene plays a role in the regulation of ubiquitination.