CYP2C19*12 Allele

Human CYP2C19*12 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19 wild-type allele, encodes cytochrome P450 2C19*12 protein. The CYP2C19*12 allele exhibits a clinically-relevant SNP (c.1473A>C) in exon 9 that results in a X491C coding change. This alteration yields an unstable cytochrome P450 2C19*12 protein that is predicted to have an additional 26 amino acids. (NCI Thesaurus)

YOU MAY ALSO LIKE

CYP2C19*10 Allele

Human CYP2C19*10 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19…

CYP2C19*1 Allele

Human CYP2C19*1 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19…

CYP2C19 wt Allele

Human CYP2C19 wild-type allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, which encodes cytochrome P450 2C19…

CYP2C19 Gene

This gene is involved in the metabolism of drugs and xenobiotics.

CYP2C18 wt Allele

Human CYP2C18 wild-type allele is located within 10q24 and is approximately 53 kb in length. This allele, which encodes cytochrome P450 2C18…

CYP2C18 Gene

This gene plays a role in the metabolism of fatty acids, tryptophan, drugs and xenobiotics.