Health / Medical Topics

    CYP2C8 wt Allele

    Human CYP2C8 wild-type allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, which encodes cytochrome P450 2C8 protein, plays a role in the metabolism of drugs and xenobiotics. Several allelic variants of the CYP2C8 gene contribute to the poor metabolizer phenotype. (NCI Thesaurus)




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