Health / Medical Topics |
CYP2C8 wt Allele
Human CYP2C8 wild-type allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, which encodes cytochrome P450 2C8 protein, plays a role in the metabolism of drugs and xenobiotics. Several allelic variants of the CYP2C8 gene contribute to the poor metabolizer phenotype. (NCI Thesaurus)
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This gene plays a role in drug metabolism. It is also involved in the oxidation of both endobiotics and xenobiotics.
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