Health / Medical Topics

    CYP2C9*18 Allele

    Human CYP2C9*18 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9 wild-type allele, encodes cytochrome P450 2C9*18 protein. The CYP2C9*18 allele exhibits a clinically-relevant SNP (c.1190A>C) in exon 8 that results in a D397A coding change. This alteration in protein sequence decreases the in vivo enzymatic activity of the cytochrome P450 2C9*18 protein. (NCI Thesaurus)




    YOU MAY ALSO LIKE

    Human CYP2C9*16 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9…
    Human CYP2C9*12 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9…
    Human CYP2C9*11 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9…
    Human CYP2C9*1 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9…
    Human CYP2C9 wild-type allele is located within 10q24 and is approximately 33 kb in length. This allele, which encodes cytochrome P450 2C9…
    This gene is involved in the oxidation of drugs, xenobiotics, fatty acids and steroids.

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact