Health / Medical Topics |
Cystine/Glutamate Transporter Protein
Cystine/glutamate transporter protein (501aa, ~55 kDa) is encoded by the human SLC7A11 gene. This protein is involved in the exchange of anionic amino acids and has a high specificity for anionic forms of cystine and glutamate. The protein has been identified as a method of entry utilized by the Karposi's sarcoma herpesvirus to gain entry into the cell. The virus plays an essential role in the pathogenesis of Karposi's sarcoma and certain types of lymphoma. (NCI Thesaurus)
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