| Health / Medical Topics |
Cytarabine Hydrochloride
The hydrochloride form of cytarabine, an antimetabolite analogue of cytidine with a modified sugar moiety (arabinose instead of ribose). Cytarabine is converted to the triphosphate form within the cell and then competes with cytidine for incorporation into DNA. Because the arabinose sugar sterically hinders the rotation of the molecule within DNA, DNA replication ceases, specifically during the S phase of the cell cycle. This agent also inhibits DNA polymerase, resulting in a decrease in DNA replication and repair. (NCI Thesaurus)
YOU MAY ALSO LIKE
A drug used to treat certain types of leukemia and prevent the spread of leukemia to the meninges (three thin layers of…
Surgery to remove the bladder (the organ that holds urine) and urethra (the tube through which urine leaves the body).
Surgical creation of an opening (stoma) for drainage of the urinary bladder.
Examination of the bladder and urethra using a cystoscope, inserted into the urethra. A cystoscope is a thin, tube-like instrument with a…
A thin, tube-like instrument used to look inside the bladder and urethra. A cystoscope has a light and a lens for viewing…
A type of tumor found in breast or prostate tissue. It is often large and bulky and grows quickly. It may be…
