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CYTOSKELETON
Pronunciation (US): | (GB): |
I. (noun)
Sense 1
Meaning:
A microscopic network of actin filaments and microtubules in the cytoplasm of many living cells that gives the cell shape and coherence
Classified under:
Hypernyms ("cytoskeleton" is a kind of...):
anatomical structure; bodily structure; body structure; complex body part; structure (a particular complex anatomical part of a living thing and its construction and arrangement)
Holonyms ("cytoskeleton" is a part of...):
cytol; cytoplasm (the protoplasm of a cell excluding the nucleus; is full of proteins that control cell metabolism)
Context examples:
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin.
(Microtubule, NCI Thesaurus/LocusLink)
This gene plays a role in both cell adhesion and cytoskeleton modeling.
(MSN Gene, NCI Thesaurus)
This protein plays a role in both cell adhesion and connection of the cytoskeleton to the plasma membrane.
(Moesin, NCI Thesaurus)
Microfilaments physically associate with microtubules to play a structural role in cytoskeleton integrity.
(Microfilament Protein, NCI Thesaurus)
A fluid cytoplasmic substance filling the interstices of the cytoskeleton.
(Cytoplasmic Matrix, NCI Thesaurus)
This allele, which encodes moesin protein, is involved in the modulation both of cell-cell adhesion and the structure of the cytoskeleton.
(MSN wt Allele, NCI Thesaurus)
This protein plays a role in cytoskeleton rearrangement andmetastasis suppression.
(Metastasis-Suppressor KiSS-1, NCI Thesaurus)
Calpains digest the links between the actin cytoskeleton and several focal adhesion complex proteins; talin, paxillin and focal adhesion kinase.
(Calpain-2 Cell Motility Pathway, NCI Thesaurus/BIOCARTA)
The classical cadherins have five homologous extracellular domains and a cytosolic domain which binds through catenin to the cytoskeleton.
(Cadherin, NCI Thesaurus)
This allele, which encodes PDZ and LIM domain protein 4, may play a role in the modulation of the structure of the actin cytoskeleton.
(PDLIM4 wt Allele, NCI Thesaurus)