Learning / English Dictionary |
CYTOTOXIC DRUG
Pronunciation (US): | (GB): |
I. (noun)
Sense 1
Meaning:
Any drug that has a toxic effect on cells; commonly used in chemotherapy to inhibit the proliferation of cancerous cells
Classified under:
Nouns denoting man-made objects
Hypernyms ("cytotoxic drug" is a kind of...):
medicament; medication; medicinal drug; medicine ((medicine) something that treats or prevents or alleviates the symptoms of disease)
Hyponyms (each of the following is a kind of "cytotoxic drug"):
antineoplastic; antineoplastic drug; cancer drug (any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function)
Context examples:
Leukoregulin shows tumor growth inhibitory activity, enhances membrane permeability, and promotes the uptake of cytotoxic drugs by tumors cells without affecting these processes in normal cells.
(Leukoregulin, NCI Thesaurus)
Once bound to the P-gp efflux pump, dofequidar is transported out of transformed cells by a mechanism similar to that used by cytotoxic drugs, thereby blocking the efflux of these compounds from the cell.
(Dofequidar Fumarate, NCI Thesaurus)