| Health / Medical Topics |
DCC wt Allele
Definition 1
Human DCC wild-type allele is located in the vicinity of 18q21.3 and is approximately 1190 kb in length. This allele, which encodes netrin receptor DCC protein, plays a role in both axonal guidance and neuronal growth cone formation. Mutation of this gene may be associated with both colorectal and esophageal carcinomas. (NCI Thesaurus)
Definition 2
Tumor suppressor genes located in the 18q21-qter region of human chromosome 18. The absence of these genes is associated with the formation of colorectal cancer (DCC stands for deleted in colorectal cancer). The products of these genes show significant homology to neural cell adhesion molecules and other related cell surface glycoproteins. (NLM, Medical Subject Headings)
YOU MAY ALSO LIKE
This gene plays a role in the regulation of several processes that determine neuronal cell morphology.
Human DCAF7 wild-type allele is located in the vicinity of 17q23.3 and is approximately 44 kb in length. This allele, which encodes…
This gene may play a role in regulation of transcription.
An autologous, multivalent dendritic cell vaccine targeting ovarian cancer with potential immunostimulating and antineoplastic activities. DC-OVA vaccine is produced in vitro by…
A cationic cholesterol derivative mixed with dimethylaminoethane-carbamoyl and sonicated to form small unilamellar vesicles that can complex with DNA, DNA/protein complexes and…
An abbreviation for a chemotherapy combination used with radiation therapy to treat childhood Hodgkin lymphoma. It includes the drugs doxorubicin hydrochloride (Adriamycin),…
