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    DEACTIVATION

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    The act of deactivating or making ineffective (as a bomb)play

    Synonyms:

    deactivation; defusing

    Classified under:

    Nouns denoting acts or actions

    Hypernyms ("deactivation" is a kind of...):

    conclusion; ending; termination (the act of ending something)

    Antonym:

    activation (making active and effective (as a bomb))

    Derivation:

    deactivate (make inactive)

    Sense 2

    Meaning:

    Breaking up a military unit (by transfers or discharges)play

    Synonyms:

    deactivation; inactivation

    Classified under:

    Nouns denoting acts or actions

    Hypernyms ("deactivation" is a kind of...):

    discharge; dismissal; dismission; firing; liberation; release; sack; sacking (the termination of someone's employment (leaving them free to depart))

    Domain category:

    armed forces; armed services; military; military machine; war machine (the military forces of a nation)

    Derivation:

    deactivate (remove from active military status or reassign)

    Credits

     Context examples: 

    The activation of p35 by Map kinase pathways followed by deactivation of Map kinase signaling by the Cdk5/p35 complex completes the loop of a feedback circuit to terminate Map kinase signaling.

    (MAP Kinase Downregulation Pathway, NCI Thesaurus/BIOCARTA)

    This allele, which encodes G protein-coupled receptor kinase 7 protein, is involved in deactivation of cone opsins in the retina.

    (GRK7 wt Allele, NCI Thesaurus)

    Any substance that inhibits hydroxysteroid dehydrogenase, an enzyme that catalyzes the interconversion of hydroxyl and carboxyl groups on steroids, leading to activation or deactivation of the steroid molecule.

    (Hydroxysteroid Dehydrogenase Inhibitor, NCI Thesaurus)

    Upon specific, high-affinity binding to IL-4 receptors located on the tumor cell surface., IL4-Pseudomonas exotoxin fusion protein PRX321 is internalized; the exotoxin moiety then binds to translation elongation factor 2 (EF-2), which may result in ADP ribosylation, deactivation of EF-2, inhibition of protein synthesis, and tumor cell apoptosis.

    (IL4-Pseudomonas Exotoxin Fusion Protein PRX321, NCI Thesaurus)

    The research team measured the processes of current pathway formation, retention and deactivation while electric current was flowing through the network and found that these processes always fluctuate as they progress, similar to the human brain’s memorization, learning, and forgetting processes.

    (Neuromorphic Metallic Nanowire Network Shows Human Brain-Like Functions, The Titi Tudorancea Bulletin)

    Recovery from light involves the deactivation of the light-activated intermediates: photolyzed rhodopsin is phosphorylated by rhodopsin kinase (RK) and subsequently capped off by arrestin; GTP-binding transducin alpha subunit deactivates through a process that is stimulated by RGS9.

    (Phototransduction Pathway, NCI Thesaurus/KEGG)


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