Health / Medical Topics |
Decitabine
Pronunciation
Definition 1
A drug that is used to treat myelodysplastic syndromes and is being studied in the treatment of other types of cancer. It is a type of antimetabolite. Also called Dacogen. (NCI Dictionary)
Definition 2
A cytidine antimetabolite analogue with potential antineoplastic activity. Decitabine incorporates into DNA and inhibits DNA methyltransferase, resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. (NCI Thesaurus)
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