| Health / Medical Topics |
Defibrotide
Pronunciation
Definition 1
A substance that is being studied in the prevention of veno-occlusive disease, a rare complication of high-dose chemotherapy and stem cell transplantation in which small veins in the liver become blocked. (NCI Dictionary)
Definition 2
A polydeoxyribonucleotide with antithrombotic, thrombolytic, and fibrinolytic properties. Defibrotide induces the release of prostaglandin 12 and reduces the expression of adhesion molecules on endothelial cells, thereby interfering with platelet and leukocyte adhesion to the endothelium. (NCI Thesaurus)
YOU MAY ALSO LIKE
An electronic device designed to deliver a controlled electric shock to the heart in order to restore a normal heart rhythm, as…
The part of a defibrillator designed to be placed in contact with the body.
The lowest energy where a defibrillator device terminates an arrhythmia in a particular subject.
Closely watching a patient’s condition but not giving treatment unless symptoms appear or change, or there are changes in test results. Deferred…
The mesylate salt of an iron-chelating agent that binds free iron in a stable complex, preventing it from engaging in chemical…
The hydrochloride salt form of deferoxamine, an iron chelating agent. Deferoxamine chelates iron from intra-lysosomal ferritin and hemosiderin forming ferrioxamine, a…
