Dendrimer

A dendrimer is a tree-like highly branched polymer molecule (Greek dendra = tree). Dendrimers are synthesized from monomers with new branches added in discrete steps ("generation") to form a tree-like architecture. A high level of synthetic control is achieved through step-wise reactions and purifications at each step to control the size, architecture, functionality and monodispersity. Several different kinds of dendrimers have been synthesized utilizing different monomers and some are commercially available.

Dendrimers are of particular interest for cancer applications because of their defined and reproducible size, but more importantly, because it is easy to attach a variety of other molecules to the surface of a dendrimer. Such molecules could include tumor-targeting agents (including but not restricted to monoclonal antibodies), imaging contrast agents to pinpoint tumors, drug molecules for delivery to a tumor, and reporter molecules that might detect if an anticancer drug is working.

Source: National Cancer Institute (U.S.)

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Demographics Domain

A subject domain utilized for the submission of information encompassing and representing data, vocabulary or records related to demographics.

Demographics Date of Collection

The date on which the subject demographics are taken.

Demographics Data Collection Day

The day of the week demographics data was collected.