Library / English Dictionary

DEOXYCYTIDINE

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

A nucleoside component of DNA; composed of cytosine and deoxyribose

Synonyms:

cytidine; deoxycytidine

Classified under:

Nouns denoting substances

Hypernyms ("deoxycytidine" is a kind of...):

nucleoside (a glycoside formed by partial hydrolysis of a nucleic acid)

Credits

 Context examples: 

Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP.

(Fludarabine phosphate, NCI Thesaurus)

FdCyd is coadministered with tetrahydrouridine (THU), an inhibitor of cytidine/deoxycytidine deaminase, which prevents FdCyd breakdown and increases its efficacy.

(Fluorine F 18 5-Fluoro-2-deoxycytidine, NCI Thesaurus)

The presence of deoxycytidine kinase in a tumor is a determinant of tumor sensitivity to this drug.

(Fazarabine, NCI Thesaurus)

An anhydrous form of cidofovir, a synthetic, acyclic monophosphate nucleotide analog of deoxycytidine with antiviral activity, mostly used against cytomegalovirus (CMV).

(Cidofovir Anhydrous, NCI Thesaurus)

A synthetic, acyclic, monophosphate nucleotide analog of deoxycytidine with antiviral activity, and mostly used against cytomegalovirus (CMV).

(Cidofovir, NCI Thesaurus)

Upon administration, ancitabine is slowly hydrolyzed into cytarabine, which is converted to the active triphosphate form and competes with deoxycytidine triphosphate for incorporation into DNA.

(Ancitabine, NCI Thesaurus)

Any substance that inhibits cytidine deaminase, an enzyme that scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

(Cytidine Deaminase Inhibitor, NCI Thesaurus)

In addition, this formulation of gemcitabine may be less susceptible to deamination and deactivation by deoxycytidine deaminase.

(Gemcitabine Elaidate, NCI Thesaurus)

This protein is involved in the deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively.

(Cytidine Deaminase, NCI Thesaurus)

Also called 5-fluoro-2-deoxycytidine.

(FdCyd, NCI Dictionary)