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DEPENDENT ON
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I. (adjective)
Sense 1
Meaning:
Being determined by conditions or circumstances that follow
Example:
arms sales contingent on the approval of congress
Synonyms:
contingent; contingent on; contingent upon; dependant on; dependant upon; dependent on; dependent upon; depending on
Classified under:
Similar:
conditional (imposing or depending on or containing a condition)
Context examples:
Cefprozil's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane.
(Cefprozil, NCI Thesaurus)
This leads to an inhibition of the normal functioning of these enzymes that are dependent on free sulfhydryl groups for their activity.
(Dimercaprol, NCI Thesaurus)
A person may be dependent on more than one drug.
(Drug Dependence, NCI Thesaurus)
Binding of extracellular ligand to Notch also induces cleavage at the transmembrane region by a gamma-secretase activity that is dependent on presenilin-1.
(Notch Proteolysis and Signaling Pathway, NCI Thesaurus/BIOCARTA)
Relative to other cell types, lypmocytes are highly dependent on salvage and de novo synthesis of guanine nucleotides, thus making these cells prone to MPA cytotoxicity.
(Mycophenolate Sodium, NCI Thesaurus)
Deletion of the Src-1 gene or Tif2 gene in mice reduced the response to steroid hormones and development dependent on these hormones.
(Obesity and Thermogenesis Pathway, NCI Thesaurus/BIOCARTA)
This stabilization is dependent on the RAS/RAF/MAPK pathway, which appears to inhibit the proteasome-dependent degradation of MYC.
(p21 H-Ras Protein, NCI Thesaurus)
Clinical course is dependent on effective treatment of underlying cause.
(Parinaud Syndrome, NCI Thesaurus)
MPA displays high lymphocyte specificity and cytotoxicity because lymphocyte metabolism is highly dependent on both salvage and de novo synthesis of guanine nucleotides.
(Mycophenolate, NCI Thesaurus)
Chemotherapy is rare and surgical management is generally dependent on the genetic expression in individual patients.
(Multiple Endocrine Neoplasia Type 1, NLM, Medical Subject Headings)
