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DEPRIVATION
Pronunciation (US): | (GB): |
I. (noun)
Sense 1
Meaning:
Act of depriving someone of food or money or rights
Example:
deprivation of civil rights
Synonyms:
deprivation; privation
Classified under:
Nouns denoting acts or actions
Hypernyms ("deprivation" is a kind of...):
social control (control exerted (actively or passively) by group action)
Hyponyms (each of the following is a kind of "deprivation"):
impoverishment; pauperisation; pauperization (the act of making someone poor)
starvation; starving (the act of depriving of food or subjecting to famine)
Derivation:
deprive (take away)
deprive (keep from having, keeping, or obtaining)
deprive (take away possessions from someone)
Sense 2
Meaning:
The disadvantage that results from losing something
Example:
losing him is no great deprivation
Synonyms:
deprivation; loss
Classified under:
Nouns denoting attributes of people and objects
Hypernyms ("deprivation" is a kind of...):
disadvantage (the quality of having an inferior or less favorable position)
Sense 3
Meaning:
Synonyms:
deprivation; neediness; privation; want
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("deprivation" is a kind of...):
impoverishment; poorness; poverty (the state of having little or no money and few or no material possessions)
Derivation:
deprive (take away)
deprive (take away possessions from someone)
Context examples:
High numbers of people are living in deprivation around the world and depression is a leading cause of disability on a global scale.
(Depression - men far more at risk than women in deprived areas, University of Cambridge)
Also called androgen deprivation and androgen suppression.
(Androgen ablation, NCI Dictionary)
Also called androgen ablation and androgen deprivation.
(Androgen suppression, NCI Dictionary)
D-methionine may be converted into the L- isomer in vivo, particularly in instances of L-methionine deprivation; both isomers have antioxidant activity which may be due, in part, to their sulfur moieties and chelating properties.
(D-methionine Formulation MRX-1024, NCI Thesaurus)
Also called water deprivation test.
(Fluid deprivation test, NCI Dictionary)
Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to chemotherapy and radiotherapy; mTOR, a serine/threonine kinase downstream of PI3K, may also be activated in a PI3K-independent fashion in response to nutrient and energy deprivation.
(PI3K/mTOR Dual Kinase Inhibitor XL765, NCI Thesaurus)
Highly expressed in secretory tissues (liver and pancreas) by human HYOU1 Gene (HSP70 Family), hypoxia-induced 999-aa (precursor) 150 kD Hypoxia Up-Regulated 1 Protein is an endoplasmic reticulum cytoprotectant in oxygen deprivation that may act as a chaperone with GRPs and participate in protein folding and secretion.
(Hypoxia Up-Regulated 1 Protein, NCI Thesaurus)
If my family are at length sensible of the deprivation to which their own conduct has, in the past, exposed them, and now desire to extend the hand of fellowship, let it not be repulsed.
(David Copperfield, by Charles Dickens)
Subsequently, the noncytotoxic prodrug 5-fluorocytosine (5-FC) is administered systemically and is deaminated by CD in FCU1- transduced tumor cells into 5-fluorouracil (5-FU), which is then directly metabolized to 5-fluoro-uridine monophosphate (5-FUMP) by UPRT; 5-FUMP may then be further transformed to 5-fluoro-deoxyuridine monophosphate (5-FdUMP), an irreversible inhibitor of thymidylate synthase and, so, DNA synthesis through deprivation of deoxythymidine triphosphate (dTTP). 5-FU and its active metabolites may then selectively kill tumor cells, avoiding toxicity in nonmalignant cells.
(MVA-FCU1 TG4023, NCI Thesaurus)
"Knowing that there are lower amounts of polyunsaturated fatty acids in the brain, we may need to rethink how this acid impacts brain health and conditions like oxygen deprivation."
(Discovery Challenges Belief about Brain's Cellular Makeup, The Titi Tudorancea Bulletin)