| Health / Medical Topics |
Dihydropyrimidine Dehydrogenase Inhibitor
Any substance that inhibits dihydropyrimidine dehydrogenase, a rate limiting enzyme in the degradation of pyrimidines. Inhibition of dihydropyrimidine dehydrogenase increases the biological half-life and efficacy of 5-Fluorouracil (5-FU). (NCI Thesaurus)
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