| Health / Medical Topics |
Dirty Necrosis
Definition 1
A morphologic finding indicating the presence of necrotic epithelial cells, neutrophils, karyorrhectic debris, and fibrin in the lumen of malignant glands. It was initially described in colonic adenocarcinomas, but it has also been observed in adenocarcinomas that arise in other anatomic sites, including lungs and ovaries. (NCI Thesaurus)
Definition 2
Presence of necrotic cellular debris within the lumen of the neoplastic glands in the colorectal mucosa. (NCI Dictionary)
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