| Health / Medical Topics |
DNA Damage
Drug-, radiation-induced, or spontaneous injuries to DNA that introduce deviations from its normal double-helical conformation. These changes include structural distortions that interfere with replication and transcription, as well as point mutations that disrupt base pairs and exert damaging effects on future generations through changes in DNA sequence. If the damage is minor, it can often be repaired (DNA repair); extensive damage can induce apoptosis. (NCI Thesaurus)
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A unit of measure of the concentration of deoxyribonucleic acid (DNA) copies per unit of volume equal to one milliliter.
