| Health / Medical Topics |
DNA Library
A collection of DNA molecules that have been cloned in vectors. (NCI Thesaurus)
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DNA Intrastrand Crosslinking involves the formation of a covalent bond between two bases on the same DNA strand.
DNA Interstrand Crosslinking involves the formation of a covalent bond between two bases on different DNA strand.
DNA interstrand cross-links (ICLs) are very toxic to dividing cells, because they induce mutations, chromosomal rearrangements and cell death. A number of…
A liposomal formulation of the 24-mer oligonucleotide PNT100, with potential antineoplastic activity. PNT2258 targets and complements to untranscribed DNA sequence upstream of…
DNA Intercalation involves insertion by covalent linkage of a molecule into the double-stranded deoxyribonucleotide polymer between the internal purine and pyrimidine base…
Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore…
