| Health / Medical Topics |
DNA Major Groove Binding
DNA Major Groove Binding involves temporary non-covalent interaction through intermolecular physical forces of attraction by a protein or low molecular weight ligand with double-stranded DNA in the larger (major) groove formed between successive turns by the double helical structure, in either a sequence dependent or independent fashion. (NCI Thesaurus)
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The joining together of two or more nucleic acid molecules by the action of ligase
DNA ligase 4 (911 aa, ~104 kDa) is encoded by the human LIG4 gene. This protein plays a role in non-homologous end…
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A family of enzymes that catalyze the formation of phosphodiester bonds to repair broken strands of DNA.
