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DNA Major Groove Binding Agent
An agent that binds to the major groove of DNA, interfering with DNA replication. (NCI Thesaurus)
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DNA Major Groove Binding involves temporary non-covalent interaction through intermolecular physical forces of attraction by a protein or low molecular weight ligand…
A DNA Maintenance Process consists of activities of biologic molecules, complexes, or subcellular components that preserve DNA integrity through faithful DNA replication,…
DNA Maintenance involves cellular mechanisms that maintain DNA integrity. In many organisms, maintenance of DNA integrity requires not only faithful DNA replication,…
The joining together of two or more nucleic acid molecules by the action of ligase
DNA ligase 4 (911 aa, ~104 kDa) is encoded by the human LIG4 gene. This protein plays a role in non-homologous end…
DNA ligase 1 (919 aa, ~102 kDa) is encoded by the human LIG1 gene. This protein plays a role in DNA replication…
