Health / Medical Topics |
DNA Replication Proofreading
A function of the mismatch repair (MMR) system that promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication. This function is critically dependent on the assembly of multimeric complexes involved in mismatch recognition and signal transduction to downstream repair events. (NCI Thesaurus)
YOU MAY ALSO LIKE
A complex network of interacting proteins and enzymes is required for DNA replication. Generally, DNA replication follows a multistep enzymatic pathway. At…
DNA replication licensing factor MCM7 (8719 aa, ~81 kDa) is encoded by the human MCM7 gene. This protein plays a role in…
DNA replication licensing factor MCM6 (821 aa, ~93 kDa) is encoded by the human MCM6 gene. This protein is involved in DNA…
DNA replication licensing factor MCM5 (734 aa, ~82 kDa) is encoded by the human MCM5 gene. This protein plays a role in…
DNA replication licensing factor MCM4 (863 aa, ~97 kDa) is encoded by the human MCM4 gene. This protein is involved in the…
DNA replication licensing factor MCM3 (808aa, ~91 kDa) is encoded by the human MCM3 gene. This protein is involved in the modulation…