| Health / Medical Topics |
Dolasetron
Definition 1
An indole derivative and a potent serotonin 5-HT3 receptor antagonist with anti-emetic property. Dolasetron blocks the activity of serotonin released from the enterochromaffin cells of the small intestine by selectively inhibiting and inactivating 5-HT3 receptors located on the nerve terminals of the vagus nerve in the periphery and centrally in the chemoreceptor trigger zone of the area postrema. This results in suppression of signalling to trigger chemo- and radiotherapy induced nausea and vomiting. (NCI Thesaurus)
Definition 2
The active ingredient in a drug used to treat nausea and vomiting caused by cancer treatment. Dolasetron is a type of serotonin receptor antagonist and a type of antiemetic. (NCI Dictionary)
YOU MAY ALSO LIKE
Human DOK1 wild-type allele is located in the vicinity of 2p13 and is approximately 3 kb in length. This allele, which encodes…
This gene plays a role in signal transduction and negative regulation of cell proliferation.
A family of proteins that contain both an IRS-type phosphotyrosine binding domain and a pleckstrin homology domain.
A procedure that uses light waves to create 2-dimensional (2-D) or 3-dimensional (3-D) pictures of tissues inside the body. DOI may be…
The determination of the number of Dohle bodies present in a sample.
Human DOHH wild-type allele is located in the vicinity of 19p13.3 and is approximately 10 kb in length. This allele, which encodes…
