Health / Medical Topics |
Dominant-Negative Mutation Abnormality
An alteration in a DNA sequence from a eukaryotic or a prokaryotic organism that results in the expression of a variant gene product that inhibits the function of the related wild-type gene product in heterozygotes. This type of abnormality is typically heritable, although it can also occur somatically. (NCI Thesaurus)
YOU MAY ALSO LIKE
Any mutation that encodes an altered gene product that acts to antagonize the wild-type allele. Dominant negative mutations are characterized by a…
A Dominant Negative Receptor inhibits the function of an associated protein, typically an alternate form of the same type receptor.
Exercising influence or control.
Domestic violence is a type of abuse. It usually involves a spouse or partner, but it can also be a child, elderly…
The name for a short-haired cat that does not have a pedigree nor belong to a specific cat breed. The domestic short-hair…
Indicates a person who is a member of an unmarried couple, including same sex couples, living together in longstanding relationships, that are…